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Complete, up-to-date coverage of the broad area of nucleic acid chemistry and biology Assembling contributions from a collection of authors with expertise in all areas of nucleic acids, medicinal chemistry, and therapeutic applications, Medicinal Chemistry of Nucleic...
Editeur :
Wiley
Parution :
2011-08-10
Collection :
Wiley Series in Drug Discovery and Development
PDF, ePub
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The book addresses the basics, applications, and manufacturing of plasmid biopharmaceuticals.The survey of the most relevant characteristics of plasmids provides the basics for designing plasmid products (applications) and processes (manufacturing). Key features that...
Editeur :
Wiley
Parution :
2011-08-04
PDF, ePub
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This book overviews and integrates the business and technical issues that pharmaceutical companies need to know in order to combat the major global problem of counterfeit medicines. In addition to discussion of the problems, the author Davison addresses analytical...
Editeur :
Wiley
Parution :
2011-08-04
PDF, ePub
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Drug discrimination: a practical guide to its contributions to the invention of new chemical entities and evaluations of new or known pharmacological agentsDrug discrimination can be described as a "drug detection" procedure that uses a pharmacologically active agent as...
Editeur :
Wiley
Parution :
2011-08-04
PDF, ePub
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Understand and assess the design, delivery, and efficacy of orally administered drugs A practical guide to understanding oral bioavailability, one of the major hurdles in drug development and delivery, Oral Bioavailability: Basic Principles, Advanced Concepts, and...
Editeur :
Wiley
Parution :
2011-08-04
Collection :
Wiley Series in Drug Discovery and Development
PDF, ePub
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In this ground-breaking practical reference, the family of aspartic acid proteases is described from a drug developer's perspective. The first part provides a general introduction to the family of aspartic acid proteases, their physiological functions, molecular...
Editeur :
Wiley-VCH
Parution :
2011-08-04
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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Discover new and emerging applications for microdialysis in drug evaluation Microdialysis is a highly valuable sampling tool that can be used in vivo to measure free, unbound analyte concentrations located in interstitial and extracellular spaces. This book explores the...
Editeur :
Wiley
Parution :
2011-07-13
PDF, ePub
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This book focuses on new small molecule approaches to combat viral infections. The chapters describe the discovery and development from bench through the clinic of relatively recently-approved antiviral drugs and compounds in advanced clinical development. Organized by...
Editeur :
Wiley
Parution :
2011-07-08
ePub
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Are you about to sit your pharmacology exams? Do you lack confidence in prescribing? Would it help to have a quick reference, pocket-sized reassurance on common drugs and the conditions that they are used in? The Hands-on Guide to Clinical Pharmacology is the perfect...
Editeur :
Wiley-Blackwell
Parution :
2011-06-15
Collection :
Hands-on Guides
PDF, ePub
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The definitive book on the neutralization of recombinant biopharmaceuticals Recombinant biopharmaceuticals are an important tool for treating a range of illnesses; however, their efficacy can be severely impaired by their immunogenicity. When introduced into the body,...
Editeur :
Wiley
Parution :
2011-06-09
PDF, ePub
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Drug discovery is all about finding small molecules that interact in a desired way with larger molecules, namely proteins and other macromolecules in the human body. If the three-dimensional structures of both the small and large molecule are known, their interaction...
Editeur :
Wiley-VCH
Parution :
2011-03-31
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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This book examines genotoxic impurities and their impact on the pharmaceutical industry. Specific sections examine this from both a toxicological and analytical perspective. Within these sections, the book defines appropriate strategies to both assess and ultimately...
Editeur :
Wiley
Parution :
2011-03-29
ePub
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By focusing on general molecular mechanisms of antiviral drugs rather than therapies for individual viruses, this ready reference provides the critical knowledge needed to develop entirely novel therapeutics and to target new viruses. It begins with a general discussion...
Editeur :
Wiley-VCH
Parution :
2011-03-16
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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A must-have guide for any professional in the drug manufacturing industry The Good Clinical Practice (GCP) audit is a tedious but necessary exercise that assures that all parties do their job properly and in compliance with the applicable FDA code. Clinical Trials...
Editeur :
Wiley
Parution :
2011-03-01
PDF
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RNA Interference: Application to Drug Discovery and Challenges to Pharmaceutical Development provides a general overview of this rapidly emerging field, with a strong emphasis on issues and aspects that are important to a drug development team. The first part covers...
Editeur :
Wiley
Parution :
2011-03-01
ePub
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The focus of early drug development has been the submission of an Investigational New Drug application to regulatory agencies. Early Drug Development: Strategies and Routes to First-in-Human Trials guides drug development organizations in preparing and submitting an...
Editeur :
Wiley
Parution :
2011-02-25
PDF, ePub
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This book guides the reader through FDA regulation guidelines and outlines a comprehensive strategy for cost reduction in regulatory affairs and compliance.This book explains six strategies to cost-effectively comply with FDA regulations while maintaining product safety...
Editeur :
Wiley
Parution :
2011-02-11
PDF, ePub
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Over the past two decades the benefits of label-free biosensor analysis have begun to make an impact in the market, and systems are beginning to be used as mainstream research tools in many drug discovery laboratories. Label-Free Technologies For Drug Discovery...
Editeur :
Wiley
Parution :
2011-01-31
PDF, ePub
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This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational...
Editeur :
Wiley-VCH
Parution :
2011-01-11
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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This book gives pharmaceutical scientists an up-to-date resource on protein aggregation and its consequences, and available methods to control or slow down the aggregation process. While significant progress has been made in the past decade, the current understanding of...
Editeur :
Wiley
Parution :
2010-12-28
ePub
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