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This first systematic treatment of the concept and practice of scaffold hopping shows the tricks of the trade and provides invaluable guidance for the reader's own projects. The first section serves as an introduction to the topic by describing the concept of...
Editeur :
Wiley-VCH
Parution :
2013-11-06
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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Cost-effective strategies for designing novel drug delivery systems that target a broad range of disease conditions In vivo imaging has become an important tool for the development of new drug delivery systems, shedding new light on the pharmacokinetics,...
Editeur :
Wiley
Parution :
2013-10-14
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Systematically examining current methods and strategies, this ready reference covers a wide range of molecular structures, from organic-chemical drugs to peptides, Proteins and nucleic acids, in line with emerging new drug classes derived from biomacromolecules. A...
Editeur :
Wiley-VCH
Parution :
2013-10-10
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Written for drug developers rather than computer scientists, this monograph adopts a systematic approach to mining scientifi c data sources, covering all key steps in rational drug discovery, from compound screening to lead compound selection and personalized medicine....
Editeur :
Wiley-VCH
Parution :
2013-09-25
Collection :
Methods & Principles in Medicinal Chemistry
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Most of the antibiotics now in use have been discovered more or less by chance, and their mechanisms of action have only been elucidated after their discovery. To meet the medical need for next-generation antibiotics, a more rational approach to antibiotic development...
Editeur :
Wiley-VCH
Parution :
2013-09-04
PDF, ePub
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Throughout history, humans everywhere have searched for remedies to heal our bodies and minds. Covering everything from ancient herbs to cutting-edge chemicals, this book in the hugely popular Milestones series looks at 250 of the most important moments in the...
Editeur :
Union Square & Co.
Parution :
2013-09-03
Collection :
Union Square & Co. Milestones
ePub
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This comprehensive, unified text on the principles and practice of clinical trials presents a detailed account of how to conduct the trials. It describes the design, analysis, and interpretation of clinical trials in a non-technical manner and provides a general...
Editeur :
Wiley
Parution :
2013-07-17
PDF, ePub
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Textbook of Pharmacoepidemiology, Second Edition, provides an introduction to pharmacoepidemiology and the data sources, methods and applications used in clinical research, the pharmaceutical industryand regulatory agencies. Drawing upon the fifth edition of the...
Editeur :
Wiley-Blackwell
Parution :
2013-07-08
PDF, ePub
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Most medicines have never been adequately tested for safety and efficacy in pediatric populations and preterm, infants and children are particularly vulnerable to adverse drug reactions.Pediatric Drug Development: Concepts and Applications, Second Edition, addresses the...
Editeur :
Wiley-Blackwell
Parution :
2013-05-20
PDF, ePub
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The latest edition of this highly acclaimed textbook, provides a comprehensive and up-to-date overview of the science and medical applications of biopharmaceutical products. Biopharmaceuticals refers to pharmaceutical substances derived from biological sources, and...
Editeur :
Wiley-Blackwell
Parution :
2013-04-29
ePub
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The Textbook of Pharmaceutical Medicine is the standard reference for everyone working and learning in pharmaceutical medicine. It is a comprehensive resource covering the processes and practices by which medicines are developed, tested and approved, and the recognised...
Editeur :
BMJ Books
Parution :
2013-03-29
PDF, ePub
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Quantitative Research Methods for Health Professionals: A Practical Interactive Course is a superb introduction to epidemiology, biostatistics, and research methodology for the whole health care community. Drawing examples from a wide range of health research, this...
Editeur :
Wiley-Interscience
Parution :
2013-03-18
PDF
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"The goal is to provide a comprehensive reference book for the preclinicaldiscovery and development scientist whose responsibilities span target identification, lead candidate selection, pharmacokinetics, pharmacology, and toxicology, and for regulatory scientists whose...
Editeur :
Wiley-Interscience
Parution :
2013-03-07
PDF, ePub
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Nonclinical Safety AssessmentNonclinical Safety Assessment A Guide to International Pharmaceutical Regulations Bringing a new drug to market is a costly time-consuming process. Increased regional and international regulation over the last twenty years, while...
Editeur :
Wiley
Parution :
2013-03-05
PDF, ePub
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Important safety aspects of compatibility for therapeutic products and their manufacturing systems, delivery devices, and containers Compatibility of Pharmaceutical Products and Contact Materials helps pharmaceutical, toxicology, analytical, and regulatory affairs...
Editeur :
Wiley-Interscience
Parution :
2013-02-26
PDF, ePub
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Die pharmazeutische Mikrobiologie hat sich in den letzten Jahrzehnten von einer hochspezialisierten Wissenschaft zu einer Querschnittdisziplin entwickelt, die fur Pharmazeuten, Mikrobiologen, aber auch Mediziner und Qualitatssicherungsbeauftragte von fundamentaler...
Editeur :
Wiley-VCH
Parution :
2013-02-11
PDF, ePub
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The need for novel antibiotics is greater now than perhaps any time since the pre-antibiotic era. Indeed, the recent collapse of many pharmaceutical antibacterial groups, combined with the emergence of hypervirulent and pan-antibiotic-resistant bacteria has severely...
Editeur :
Wiley-Blackwell
Parution :
2013-01-14
Collection :
Life Science Research Fundamentals
ePub
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Treating protein-protein interactions as a novel and highly promising class of drug targets, this volume introduces the underlying strategies step by step, from the biology of PPIs to biophysical and computational methods for their investigation. The main part of the...
Editeur :
Wiley-VCH
Parution :
2013-01-02
Collection :
Methods & Principles in Medicinal Chemistry
PDF, ePub
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An expert's view on solving the challenges confronting today's pharmaceutical industry Author John LaMattina, a thirty-year veteran of the pharmaceutical industry and former president of Pfizer's Global R&D Division, is internationally recognized as an expert on the...
Editeur :
Wiley
Parution :
2012-12-10
PDF, ePub
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Sets forth the state of the science and technology in plasma protein production With contributions from an international team of eighty leading experts and pioneers in the field, Production of Plasma Proteins for Therapeutic Use presents a comprehensive overview of the...
Editeur :
Wiley
Parution :
2012-12-06
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